Research

What the evidence actually says.

Stopping GLP-1: What to Expect for Weight, Appetite, and Labs

October 20, 2026

Stopping GLP-1: What to Expect for Weight, Appetite, and Labs

Research shows drug clearance, biology and behavior all matter when you stop GLP-1 medications. This guide explains timing, appetite return, metabolic markers and practical defenses.

Longevity Myths: What If the Headline Was Never in the Study?

October 8, 2026

Longevity Myths: What If the Headline Was Never in the Study?

Most longevity myths start with a real study. Follow one from the lab to the headline, then use five questions on any claim you read, including ours. Part of our series on aging.

Longevity Medicine: What If You Started With What You Want to Change?

October 8, 2026

Longevity Medicine: What If You Started With What You Want to Change?

Longevity medicine is not one treatment. It is seven, and each answers a different question. What each one is, what the studies show, who it suits and what it costs. The guide to our series on aging.

NMN vs NAD+: What If You Skipped the Ingredient and Took the Real Thing?

October 7, 2026

NMN vs NAD+: What If You Skipped the Ingredient and Took the Real Thing?

NMN is the ingredient. NAD+ is the molecule your cells use. One is a capsule for the price-conscious, the other a prescription injection. What each is, what the studies show and what each costs. Part of our series on aging.

Benefits of B12 Shots: What If You Are Not Tired, Just Running Low?

October 7, 2026

Benefits of B12 Shots: What If You Are Not Tired, Just Running Low?

Tired, foggy, a little flat? It may not be your age. Many adults run low on B12 without knowing it, and a shot does not depend on your gut. Who runs low, what shots do and what they cost. Part of our series on aging.

Sermorelin and Aging: What If Your Body Only Needed a Nudge?

October 7, 2026

Sermorelin and Aging: What If Your Body Only Needed a Nudge?

Sermorelin does not add anything to your body. It prompts your own pituitary to do more of what it once did. What the studies found, what it costs and who it suits. Part of our series on aging.

Metformin for Longevity: What If It Was Never Meant to Work Alone?

October 7, 2026

Metformin for Longevity: What If It Was Never Meant to Work Alone?

Metformin is the most famous longevity drug that has never passed a longevity trial. Why it disappoints alone, what it does to NAD+, and the case for a low-dose partner. Part of our series on aging.

Glutathione Injections: What If You Could Refill Your Master Antioxidant?

October 7, 2026

Glutathione Injections: What If You Could Refill Your Master Antioxidant?

Your body makes its own antioxidant, and makes less of it with age. What happened when researchers restored it in older adults, why we favor small regular injections, and what a month costs. Part of our series on aging.

NAD+ Injections and Aging: What If You Never Ran Low?

October 7, 2026

NAD+ Injections and Aging: What If You Never Ran Low?

Mice given NAD+ boosters stay healthier for longer, and people can raise their NAD+ too. Whether that slows aging is the part nobody has tested. Here is what is known, what it costs, and how we think about it.

What Is Food Noise? Why the Thoughts Don't Switch Off

September 10, 2026

What Is Food Noise? Why the Thoughts Don't Switch Off

Persistent, unwanted thinking about food now has a formal research definition. What it is, why it isn't a willpower problem, and when it's worth getting help.

Do GLP-1 Medications Slow Aging? What the Research Shows

September 4, 2026

Do GLP-1 Medications Slow Aging? What the Research Shows

Metabolic dysfunction overlaps with several biological mechanisms of aging, and GLP-1 medications measurably improve many of them. But losing weight is not the same as extending healthspan — and the trials that failed matter as much as the ones that worked.